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March 05, 2026
Route 66 by Rail with Amtrak Vacations

Experience America’s most legendary highway in a whole new way on Route 66 by Rail with Amtrak Vacations. This expertly crafted itinerary takes you from Chicago to Los Angeles aboard Amtrak’s comfortable overnight train, blending classic Americana with effortless rail travel. Ride the Grand Canyon Railway to the Canyon’s South Rim, and tour Beverly Hills to see the homes of the stars and starlets of Los Angeles. From iconic landscapes to nostalgic Route 66 towns, this seamless adventure showcases how easy it is to discover the Southwest by train. Sit back, relax, and let Amtrak Vacations bring the spirit of Route 66 to life by rail.

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